Research workbench
Structure of 4C1 Fab in C2221 space group
Analyse Structure of 4C1 Fab in C2221 space group in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3RVU
- Type
- protein
- Length
- 433 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 4C1 Fab - light chain; 4C1 Fab - heavy chain
- Pockets
- 4 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 3% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | 4C1 Fab - light chain | protein | 212 | 6% helix, 52% strand | — |
| D | 4C1 Fab - heavy chain | protein | 221 | 1% helix, 49% strand | — |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 195 | 0.53 | 0.78 | 29 | empty |
| 2 | 305 | 0.53 | 0.75 | 48 | empty |
| 3 | 53 | 0.44 | 0.84 | 15 | empty |
| 4 | 88 | 0.35 | 0.75 | 23 | empty |
Interfaces
1 interface between chains.
- C–D · 2038 Ų buried · 26 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 3RVU · Structure of 4C1 Fab in C2221 space group · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3RVU · PDBe 3RVU
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