Research workbench
Crystal structure of conserved protein of unknown function with hot dog fold from alicyclobacillus acidocaldarius
Analyse Crystal structure of conserved protein of unknown function with hot dog fold… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3RQB
- Type
- protein
- Length
- 529 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- C8WTQ0
- Ligands
- CL
- Pockets
- 4 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 18% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 264 | 19% helix, 40% strand | C8WTQ0 |
| B | Uncharacterized protein | protein | 265 | 17% helix, 40% strand | C8WTQ0 |
Ligands and binding sites
- CL · Chloride ion · ion · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 575 | 0.79 | 0.85 | 69 | empty |
| 2 | 545 | 0.76 | 0.83 | 72 | CL |
| 3 | 171 | 0.42 | 0.73 | 30 | empty |
| 4 | 60 | 0.27 | 0.73 | 15 | CL |
Interfaces
1 interface between chains.
- A–B · 2923 Ų buried · 43 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 18 modified (engineered).
Compared structures
- 3RQB · Crystal Structure of Conserved Protein of Unknown Function with Hot dog Fold from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C8WTQ0
- Elsewhere: RCSB PDB 3RQB · PDBe 3RQB · UniProt C8WTQ0
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