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Crystal structure of the S. aureus protein tyrosine phosphatase ptpa

Analyse Crystal structure of the S. aureus protein tyrosine phosphatase ptpa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3ROF
Type: protein
Length: 165 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Low molecular weight protein-tyrosine-phosphatase ptpa; Expression tag cleaved from…
EC: 3.1.3.48
UniProt: P0C5D2
Ligands: PO4

Structure

x-ray diffraction · 2 distinct chains · 39% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Low molecular weight protein-tyrosine-phosphatase ptpa (EC 3.1.3.48)	protein	158	41% helix, 15% strand	P0C5D2
B	Expression tag cleaved from protein-tyrosine-phosphatase ptpa	protein	7	0% helix, 0% strand	—

Ligands and binding sites

PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 429 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

3ROF · Crystal Structure of the S. aureus Protein Tyrosine Phosphatase PtpA · the same entry in another collection · chain A against A, TM-score 1.00
P0C5D2 · AlphaFold monomer V2.0 prediction for low molecular weight protein- tyrosine-phosphatase… · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0C5D2
Elsewhere: RCSB PDB 3ROF · PDBe 3ROF · UniProt P0C5D2

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