Research workbench
Structure of pseudomonas aeruginosa transcriptional regulator PA2196
Analyse Structure of pseudomonas aeruginosa transcriptional regulator PA2196 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3RD3
- Type
- protein
- Length
- 374 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable transcriptional regulator
- UniProt
- Q9I1S1
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Probable transcriptional regulator | protein | 187 | 74% helix, 0% strand | Q9I1S1 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 189 | 0.67 | 0.86 | 37 | empty |
| 2 | 193 | 0.60 | 0.82 | 27 | empty |
| 3 | 65 | 0.43 | 0.81 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1811 Ų buried · 20 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 3RD3 · Structure of Pseudomonas aeruginosa transcriptional regulator PA2196 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9I1S1
- Elsewhere: RCSB PDB 3RD3 · PDBe 3RD3 · UniProt Q9I1S1
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