Research workbench
Crystal structure of spire kind domain in complex with the tail of FMN2
Analyse Crystal structure of spire kind domain in complex with the tail of FMN2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3R7G
- Type
- protein
- Length
- 173 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein spire homolog 1; Formin-2
- UniProt
- Q08AE8, Q9NZ56
- Pockets
- 1 · best druggability 0.37
Structure
x-ray diffraction · 2 distinct chains · 54% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein spire homolog 1 | protein | 154 | 57% helix, 8% strand | Q08AE8 |
| B | Formin-2 | protein | 19 | 32% helix, 16% strand | Q9NZ56 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 51 | 0.37 | 0.80 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 925 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 3R7G · Crystal structure of Spire KIND domain in complex with the tail of FMN2 · the same entry in another collection · chain A against A, TM-score 1.00
- Q08AE8 · AlphaFold monomer V2.0 prediction for protein spire homolog 1 (Q08AE8) · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q9NZ56 · AlphaFold monomer V2.0 prediction for formin-2 (Q9NZ56) · a predicted model of the same protein · chain B against A, TM-score 0.40
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08AE8
- Every structure of UniProt Q9NZ56
- Elsewhere: RCSB PDB 3R7G · PDBe 3R7G · UniProt Q08AE8 · UniProt Q9NZ56
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