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Crystal structure of the archaeal holliday junction resolvase hjc

Analyse Crystal structure of the archaeal holliday junction resolvase hjc in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1GEF
Type: protein
Length: 459 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Holliday junction resolvase
UniProt: Q9V301
Ligands: SO4
Pockets: 2 · best druggability 0.81

Structure

x-ray diffraction · 4 distinct chains · 33% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Holliday junction resolvase	protein	120	36% helix, 33% strand	Q9V301
B	Holliday junction resolvase	protein	116	30% helix, 34% strand	Q9V301
D	Holliday junction resolvase	protein	109	35% helix, 30% strand	Q9V301
E	Holliday junction resolvase	protein	114	30% helix, 34% strand	Q9V301

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A, B, D, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1166	0.81	0.82	110	SO4
2	120	0.46	0.79	26	empty

Interfaces

4 interfaces between chains.

B–D · 870 Å² buried · 19 hydrogen bonds · protein-protein
A–E · 868 Å² buried · 18 hydrogen bonds · protein-protein
A–B · 663 Å² buried · 22 hydrogen bonds · protein-protein
D–E · 648 Å² buried · 23 hydrogen bonds · protein-protein

Compared structures

1GEF · Crystal structure of the archaeal holliday junction resolvase HJC · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9V301
Elsewhere: RCSB PDB 1GEF · PDBe 1GEF · UniProt Q9V301

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