Research workbench
Crystal structure of CEL5A (EG2) from hypocrea jecorina (trichoderma reesei)
Analyse Crystal structure of CEL5A (EG2) from hypocrea jecorina (trichoderma reesei) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3QR3
- Type
- protein
- Length
- 658 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endoglucanase eg-II
- EC
- 3.2.1.4
- UniProt
- P07982
- Ligands
- MG, SO4
- Pockets
- 2 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Endoglucanase eg-II (EC 3.2.1.4) | protein | 329 | 34% helix, 18% strand | P07982 |
Ligands and binding sites
- MG · Magnesium ion · metal · 4 copies · chains A, B
- SO4 · Sulfate ion · ion · 14 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 840 | 0.73 | 0.78 | 87 | SO4 |
| 2 | 134 | 0.41 | 0.75 | 23 | SO4 |
Interfaces
1 interface between chains.
- A–B · 511 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 3QR3 · Crystal Structure of Cel5A (EG2) from Hypocrea jecorina (Trichoderma reesei) · the same entry in another collection · chain A against A, TM-score 1.00
- P07982 · AlphaFold monomer V2.0 prediction for endoglucanase eg-II (P07982) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07982
- Elsewhere: RCSB PDB 3QR3 · PDBe 3QR3 · UniProt P07982
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.