Research workbench
Crystal structure of putative transcriptional regulator from yersinia pestis biovar microtus str. 91001
Analyse Crystal structure of putative transcriptional regulator from yersinia pestis… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3QK7
- Type
- protein
- Length
- 841 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulators
- UniProt
- Q74V61
- Pockets
- 12 · best druggability 0.87
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Transcriptional regulators | protein | 280 | 39% helix, 20% strand | Q74V61 |
| C | Transcriptional regulators | protein | 281 | 38% helix, 21% strand | Q74V61 |
Pockets
12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1176 | 0.87 | 0.88 | 95 | empty |
| 2 | 375 | 0.81 | 0.90 | 35 | empty |
| 3 | 953 | 0.77 | 0.80 | 94 | empty |
| 4 | 112 | 0.51 | 0.81 | 19 | empty |
| 5 | 119 | 0.50 | 0.81 | 24 | empty |
Interfaces
3 interfaces between chains.
- B–C · 1632 Ų buried · 18 hydrogen bonds · protein-protein
- A–B · 509 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 223 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 15 modified (engineered).
Compared structures
- 3QK7 · Crystal structure of putative Transcriptional regulator from Yersinia pestis biovar… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q74V61
- Elsewhere: RCSB PDB 3QK7 · PDBe 3QK7 · UniProt Q74V61
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