Research workbench
Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-SEC14 scaffold by directed evolution
Analyse Resurrection of a functional phosphatidylinositol transfer protein from a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3Q8G
- Type
- protein
- Length
- 306 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cral-trio domain-containing protein YKL091C
- UniProt
- P33324
- Ligands
- PEE
- Pockets
- 3 · best druggability 0.87
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cral-trio domain-containing protein YKL091C | protein | 306 | 52% helix, 11% strand | P33324 |
Ligands and binding sites
- PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · ligand · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 769 | 0.87 | 0.90 | 75 | PEE |
| 2 | 268 | 0.64 | 0.81 | 38 | GOL |
| 3 | 167 | 0.61 | 0.83 | 28 | empty |
Compared structures
- 3Q8G · Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14… · the same entry in another collection · chain A against A, TM-score 1.00
- P33324 · AlphaFold monomer V2.0 prediction for cral-trio domain-containing protein YKL091C (P33324) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33324
- Elsewhere: RCSB PDB 3Q8G · PDBe 3Q8G · UniProt P33324
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