Research workbench
Crystal structure of the tpr domain of chip complexed with phosphorylated SMAD1 peptide
Analyse Crystal structure of the tpr domain of chip complexed with phosphorylated SMAD1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3Q4A
- Type
- protein
- Length
- 138 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- STIP1 homology and U box-containing protein 1; SMAD1 peptide
- EC
- 6.3.2.-
- UniProt
- Q9WUD1
Structure
x-ray diffraction · 2 distinct chains · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) | protein | 132 | 77% helix, 0% strand | Q9WUD1 |
| C | SMAD1 peptide | protein | 6 | 0% helix, 0% strand | — |
Interfaces
1 interface between chains.
- B–C · 510 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (phosphorylation).
Compared structures
- 3Q4A · Crystal structure of the TPR domain of CHIP complexed with phosphorylated Smad1 peptide · the same entry in another collection · chain B against B, TM-score 1.00
- Q9WUD1 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase chip (Q9WUD1) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WUD1
- Elsewhere: RCSB PDB 3Q4A · PDBe 3Q4A · UniProt Q9WUD1
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