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Methionyl-tRNA formyltransferase from vibrio cholerae

Analyse Methionyl-tRNA formyltransferase from vibrio cholerae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3Q0I
Type: protein
Length: 303 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Methionyl-tRNA formyltransferase
EC: 2.1.2.9
UniProt: Q9KVU4
Ligands: SO4
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methionyl-tRNA formyltransferase (EC 2.1.2.9)	protein	303	29% helix, 27% strand	Q9KVU4

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	319	0.56	0.76	38	GOL

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

3Q0I · Methionyl-tRNA formyltransferase from Vibrio cholerae · the same entry in another collection · chain A against A, TM-score 1.00
Q9KVU4 · AlphaFold monomer V2.0 prediction for methionyl-tRNA formyltransferase (Q9KVU4) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9KVU4
Elsewhere: RCSB PDB 3Q0I · PDBe 3Q0I · UniProt Q9KVU4

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