Research workbench

Crystal structure of maize CK2 in complex with nbc (Z1)

Analyse Crystal structure of maize CK2 in complex with nbc (Z1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3PWD
Type: protein
Length: 327 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Casein kinase II subunit alpha
EC: 2.7.11.1
UniProt: P28523
Ligands: CZ0
Pockets: 4 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Casein kinase II subunit alpha (EC 2.7.11.1)	protein	327	42% helix, 15% strand	P28523

Ligands and binding sites

CZ0 · 8-hydroxy-4-methyl-9-nitro-2H-benzo[g]chromen-2-one · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	379	0.69	0.81	45	CZ0
2	54	0.58	0.91	19	empty
3	61	0.32	0.75	15	empty
4	55	0.30	0.75	14	empty

Compared structures

3PWD · Crystal structure of maize CK2 in complex with NBC (Z1) · the same entry in another collection · chain A against A, TM-score 1.00
P28523 · AlphaFold monomer V2.0 prediction for casein kinase II subunit alpha (P28523) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P28523
Elsewhere: RCSB PDB 3PWD · PDBe 3PWD · UniProt P28523

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.