Research workbench
Crystal structure of the G2 domain of agrin from mus musculus
Analyse Crystal structure of the G2 domain of agrin from mus musculus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3PVE
- Type
- protein
- Length
- 347 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Agrin, agrin protein
- UniProt
- Q6PCM6
- Pockets
- 5 · best druggability 0.51
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Agrin, agrin protein | protein | 175 | 7% helix, 49% strand | Q6PCM6 |
| B | Agrin, agrin protein | protein | 172 | 7% helix, 47% strand | Q6PCM6 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 75 | 0.51 | 0.84 | 15 | empty |
| 2 | 79 | 0.47 | 0.82 | 15 | empty |
| 3 | 130 | 0.47 | 0.78 | 29 | empty |
| 4 | 142 | 0.45 | 0.77 | 27 | empty |
| 5 | 88 | 0.36 | 0.76 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 745 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 3PVE · Crystal structure of the G2 domain of Agrin from Mus Musculus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6PCM6
- Elsewhere: RCSB PDB 3PVE · PDBe 3PVE · UniProt Q6PCM6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.