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Structure of legionella fallonii degq (N189G/P190G variant)

Analyse Structure of legionella fallonii degq (N189G/P190G variant) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3PV5
Type: protein
Length: 1,538 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Degq
Pockets: 20 · best druggability 0.78

Structure

x-ray diffraction · 4 distinct chains · 19% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Degq	protein	392	19% helix, 40% strand	—
B	Degq	protein	383	20% helix, 41% strand	—
C	Degq	protein	384	19% helix, 40% strand	—
D	Degq	protein	379	20% helix, 41% strand	—

Pockets

20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	228	0.78	0.91	61	empty
2	967	0.74	0.77	92	empty
3	538	0.61	0.74	39	empty
4	242	0.61	0.80	27	empty
5	270	0.60	0.79	28	empty

Interfaces

5 interfaces between chains.

B–C · 927 Å² buried · 13 hydrogen bonds · protein-protein
C–D · 866 Å² buried · 9 hydrogen bonds · protein-protein
A–C · 858 Å² buried · 11 hydrogen bonds · protein-protein
B–D · 720 Å² buried · 8 hydrogen bonds · protein-protein
A–D · 665 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

3PV5 · Structure of Legionella fallonii DegQ (N189G/P190G variant) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3PV5 · PDBe 3PV5

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