Research workbench
Crystal structure of SERINE/THREONINE phosphatase sphaerobacter thermophilus dsm 20745
Analyse Crystal structure of SERINE/THREONINE phosphatase sphaerobacter thermophilus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3PU9
- Type
- protein
- Length
- 472 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein SERINE/THREONINE phosphatase
- UniProt
- D1C2D8
- Ligands
- MG
- Pockets
- 5 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Protein SERINE/THREONINE phosphatase | protein | 236 | 26% helix, 35% strand | D1C2D8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 121 | 0.77 | 0.96 | 32 | empty |
| 2 | 118 | 0.54 | 0.83 | 25 | empty |
| 3 | 97 | 0.47 | 0.81 | 23 | GOL |
| 4 | 88 | 0.37 | 0.76 | 15 | empty |
| 5 | 117 | 0.36 | 0.73 | 30 | empty |
Interfaces
1 interface between chains.
- A–B · 2509 Ų buried · 53 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified (engineered).
Compared structures
- 3PU9 · Crystal structure of serine/threonine phosphatase Sphaerobacter thermophilus DSM 20745 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D1C2D8
- Elsewhere: RCSB PDB 3PU9 · PDBe 3PU9 · UniProt D1C2D8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.