Research workbench
Ron in complex with ligand AMP-pnp
Analyse Ron in complex with ligand AMP-pnp in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3PLS
- Type
- protein
- Length
- 298 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Macrophage-stimulating protein receptor
- EC
- 2.7.10.1
- UniProt
- Q04912
- Ligands
- ANP, MG
- Pockets
- 4 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Macrophage-stimulating protein receptor (EC 2.7.10.1) | protein | 298 | 41% helix, 16% strand | Q04912 |
Ligands and binding sites
- ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 248 | 0.60 | 0.80 | 29 | MG, ANP |
| 2 | 91 | 0.51 | 0.83 | 19 | empty |
| 3 | 53 | 0.28 | 0.74 | 13 | empty |
| 4 | 54 | 0.25 | 0.73 | 19 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q04912
- Elsewhere: RCSB PDB 3PLS · PDBe 3PLS · UniProt Q04912
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