Research workbench
Crystal structure of the hexameric replicative helicase repa of plasmid RSF1010
Analyse Crystal structure of the hexameric replicative helicase repa of plasmid RSF1010 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1G8Y
- Type
- protein
- Length
- 2,904 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulatory protein repa
- UniProt
- P20356
- Pockets
- 20 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L | Regulatory protein repa | protein | 242 | 36% helix, 19% strand | P20356 |
Pockets
20 pockets found on a 1 Å grid, 19 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 870 | 0.81 | 0.84 | 106 | empty |
| 2 | 422 | 0.73 | 0.84 | 48 | empty |
| 3 | 361 | 0.72 | 0.84 | 52 | empty |
| 4 | 355 | 0.72 | 0.84 | 54 | empty |
| 5 | 56 | 0.70 | 0.97 | 20 | empty |
Interfaces
24 interfaces between chains.
- A–F · 1689 Ų buried · 17 hydrogen bonds · protein-protein
- C–D · 1678 Ų buried · 21 hydrogen bonds · protein-protein
- A–B · 1650 Ų buried · 16 hydrogen bonds · protein-protein
- K–L · 1650 Ų buried · 24 hydrogen bonds · protein-protein
- H–I · 1647 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 1G8Y · Crystal structure of the hexameric replicative helicase repa of plasmid RSF1010 · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P20356
- Elsewhere: RCSB PDB 1G8Y · PDBe 1G8Y · UniProt P20356
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