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X-ray analysis of HIV-1 proteinase at 2.7 ångströms resolution confirms structural homology among retroviral enzymes

Analyse X-ray analysis of HIV-1 proteinase at 2.7 ångströms resolution confirms… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3PHV
Type: protein
Length: 99 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Unliganded HIV-1 protease
UniProt: P04585
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 4% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Unliganded HIV-1 protease	protein	99	4% helix, 40% strand	P04585

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	90	0.35	0.74	15	empty

Compared structures

3PHV · X-ray analysis of HIV-1 proteinase at 2.7 ångströms resolution confirms structural… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04585
Elsewhere: RCSB PDB 3PHV · PDBe 3PHV · UniProt P04585

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