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X-ray crystal structure of the second XRCC1 brct domain.

Analyse X-ray crystal structure of the second XRCC1 brct domain. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3PC6
Type: protein
Length: 202 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA repair protein XRCC1
UniProt: Q60596
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 2 distinct chains · 33% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA repair protein XRCC1	protein	99	35% helix, 15% strand	Q60596
B	DNA repair protein XRCC1	protein	103	30% helix, 15% strand	Q60596

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	134	0.41	0.74	16	empty

Interfaces

1 interface between chains.

A–B · 646 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

3PC6 · X-ray crystal structure of the second XRCC1 BRCT domain. · the same entry in another collection · chain A against A, TM-score 1.00
Q60596 · AlphaFold monomer V2.0 prediction for DNA repair protein XRCC1 (Q60596) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q60596
Elsewhere: RCSB PDB 3PC6 · PDBe 3PC6 · UniProt Q60596

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