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Alternatingly modified 2'FLUORO RNA octamer F/RA2U2-R32

Analyse Alternatingly modified 2'FLUORO RNA octamer F/RA2U2-R32 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3P4C
Type
RNA
Length
16 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5'-R(*(CFZ)P*GP*(AF2)P*AP*(UFT)P*UP*(CFZ)P*G)-3'
Ligands
SR
Pockets
1 · best druggability 0.25

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B5'-R(*(CFZ)P*GP*(AF2)P*AP*(UFT)P*UP*(CFZ)P*G)-3'rna8——

Ligands and binding sites

  • SR · Strontium ion · metal · 3 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1610.250.7312SR

Interfaces

1 interface between chains.

  • A–B · 335 Ų buried · 25 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 8 modified (nucleotide modification).

Compared structures

  • 3P4C · Alternatingly modified 2'Fluoro RNA octamer f/rA2U2-R32 · the same entry in another collection · chain A against A, TM-score 1.00

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