Research workbench

Crystal structure of a virus encoded glycosyltransferase in complex with GDP-mannose

Analyse Crystal structure of a virus encoded glycosyltransferase in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3OY7
Type: protein
Length: 784 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycosyltransferase B736L
UniProt: A7IXR1
Ligands: GDD
Pockets: 6 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Glycosyltransferase B736L	protein	392	41% helix, 18% strand	A7IXR1

Ligands and binding sites

GDD · Guanosine-5'-diphosphate-alpha-D-mannose · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	592	0.73	0.80	58	GDD
2	606	0.69	0.78	49	GDD
3	144	0.60	0.84	27	empty
4	67	0.46	0.83	19	empty
5	53	0.32	0.77	12	empty

Interfaces

1 interface between chains.

A–B · 1464 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

3OY7 · Crystal structure of a virus encoded glycosyltransferase in complex with GDP-mannose · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A7IXR1
Elsewhere: RCSB PDB 3OY7 · PDBe 3OY7 · UniProt A7IXR1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.