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Crystal structure of vaccinia virus polyadenylate POLYMERASE(VP55)
Analyse Crystal structure of vaccinia virus polyadenylate POLYMERASE(VP55) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3OWG
- Type
- protein
- Length
- 914 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- POLY(A) polymerase catalytic subunit
- EC
- 2.7.7.19
- UniProt
- P23371
- Pockets
- 3 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | POLY(A) polymerase catalytic subunit (EC 2.7.7.19) | protein | 457 | 46% helix, 15% strand | P23371 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 919 | 0.82 | 0.84 | 103 | empty |
| 2 | 614 | 0.73 | 0.80 | 43 | empty |
| 3 | 623 | 0.73 | 0.80 | 48 | empty |
Interfaces
1 interface between chains.
- A–B · 786 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 3OWG · Crystal structure of vaccinia virus Polyadenylate polymerase(vp55) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23371
- Elsewhere: RCSB PDB 3OWG · PDBe 3OWG · UniProt P23371
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