Research workbench
The secret domain in complex with CX3CL1
Analyse The secret domain in complex with CX3CL1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3ONA
- Type
- protein
- Length
- 224 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tumour necrosis factor receptor; CX3CL1 protein
- UniProt
- Q7TDW8, Q6I9S9
- Pockets
- 1 · best druggability 0.48
Structure
x-ray diffraction · 2 distinct chains · 8% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tumour necrosis factor receptor | protein | 158 | 0% helix, 48% strand | Q7TDW8 |
| B | CX3CL1 protein | protein | 66 | 26% helix, 24% strand | Q6I9S9 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 239 | 0.48 | 0.74 | 36 | empty |
Interfaces
1 interface between chains.
- A–B · 590 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 3ONA · The SECRET domain in complex with CX3CL1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7TDW8
- Every structure of UniProt Q6I9S9
- Elsewhere: RCSB PDB 3ONA · PDBe 3ONA · UniProt Q7TDW8 · UniProt Q6I9S9
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