Research workbench
Crystal structure of a pas domain from two-component sensor histidine kinase
Analyse Crystal structure of a pas domain from two-component sensor histidine kinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3OLO
- Type
- protein
- Length
- 221 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Two-component sensor histidine kinase
- EC
- 2.7.13.3
- UniProt
- Q8YZM9
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 2 distinct chains · 33% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Two-component sensor histidine kinase (EC 2.7.13.3) | protein | 111 | 34% helix, 40% strand | Q8YZM9 |
| B | Two-component sensor histidine kinase (EC 2.7.13.3) | protein | 110 | 31% helix, 41% strand | Q8YZM9 |
Ligands and binding sites
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 53 | 0.31 | 0.77 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 25 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 3OLO · Crystal structure of a PAS domain from two-component sensor histidine kinase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8YZM9
- Elsewhere: RCSB PDB 3OLO · PDBe 3OLO · UniProt Q8YZM9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.