Research workbench

Mycobacterium tuberculosis ferritin homolog, bfrb

Analyse Mycobacterium tuberculosis ferritin homolog, bfrb in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3OJ5
Type: protein
Length: 3,768 residues
Chains: 24
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ferritin family protein
UniProt: A5U9H0
Pockets: 20 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 80% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X	Ferritin family protein	protein	157	80% helix, 1% strand	A5U9H0

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.75	0.98	16	empty
2	69	0.74	0.98	15	empty
3	67	0.74	0.98	15	empty
4	66	0.74	0.98	15	empty
5	63	0.73	0.98	14	empty

Interfaces

61 interfaces between chains.

I–U · 1028 Å² buried · 12 hydrogen bonds · protein-protein
F–R · 1025 Å² buried · 13 hydrogen bonds · protein-protein
H–T · 1022 Å² buried · 13 hydrogen bonds · protein-protein
G–S · 1021 Å² buried · 12 hydrogen bonds · protein-protein
D–P · 1021 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

3OJ5 · Mycobacterium tuberculosis ferritin homolog, BfrB · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A5U9H0
Elsewhere: RCSB PDB 3OJ5 · PDBe 3OJ5 · UniProt A5U9H0

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