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F144Y/F258Y double mutant of exo-beta-1,3-glucanase from candida albicans at 2 a

Analyse F144Y/F258Y double mutant of exo-beta-1,3-glucanase from candida albicans at 2 a in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3O6A
Type: protein
Length: 394 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glucan 1,3-beta-glucosidase
EC: 3.2.1.58
UniProt: P29717
Pockets: 3 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glucan 1,3-beta-glucosidase (EC 3.2.1.58)	protein	394	39% helix, 12% strand	P29717

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	366	0.67	0.80	40	empty
2	84	0.38	0.77	24	empty
3	59	0.32	0.76	14	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

3O6A · F144Y/F258Y Double Mutant of Exo-beta-1,3-glucanase from Candida albicans at 2 A · the same entry in another collection · chain A against A, TM-score 1.00
P29717 · AlphaFold monomer V2.0 prediction for glucan 1,3-beta-glucosidase (P29717) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29717
Elsewhere: RCSB PDB 3O6A · PDBe 3O6A · UniProt P29717

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