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Crystal structure of CUGBP1 RRM1/2-RNA complex

Analyse Crystal structure of CUGBP1 RRM1/2-RNA complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3NNA
Type: protein + RNA
Length: 180 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cugbp elav-like family member 1; RNA (5'-R(*GP*UP*UP*GP*UP*UP*UP*UP*GP*UP*UP*U)-3')
UniProt: Q92879

Structure

x-ray diffraction · 2 distinct chains · 27% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cugbp elav-like family member 1	protein	175	27% helix, 31% strand	Q92879
B	RNA (5'-R(GPUPUPGPUPUPUPUPGPUPUPU)-3')	rna	5	—	—

Interfaces

1 interface between chains.

A–B · 572 Å² buried · 9 hydrogen bonds · protein-nucleic

Modifications

Observed in the structure: 10 modified (engineered).

Compared structures

3NNA · Crystal Structure of CUGBP1 RRM1/2-RNA Complex · the same entry in another collection · chain A against A, TM-score 1.00
Q92879 · AlphaFold monomer V2.0 prediction for cugbp elav-like family member 1 (Q92879) · a predicted model of the same protein · chain A against A, TM-score 0.76

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92879
Elsewhere: RCSB PDB 3NNA · PDBe 3NNA · UniProt Q92879

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