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Crystal structure of mouse bst-2/TETHERIN ectodomain

Analyse Crystal structure of mouse bst-2/TETHERIN ectodomain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3NI0
Type: protein
Length: 182 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Bone marrow stromal antigen 2
UniProt: Q8R2Q8

Structure

x-ray diffraction · 2 distinct chains · 92% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Bone marrow stromal antigen 2	protein	95	89% helix, 0% strand	Q8R2Q8
B	Bone marrow stromal antigen 2	protein	87	94% helix, 0% strand	Q8R2Q8

Ligands and binding sites

IPA · Isopropyl alcohol · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 2047 Å² buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

3NI0 · Crystal Structure of Mouse BST-2/Tetherin Ectodomain · the same entry in another collection · chain A against A, TM-score 1.00
Q8R2Q8 · AlphaFold monomer V2.0 prediction for bone marrow stromal antigen 2 (Q8R2Q8) · a predicted model of the same protein · chain B against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8R2Q8
Elsewhere: RCSB PDB 3NI0 · PDBe 3NI0 · UniProt Q8R2Q8

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