Research workbench
Structure of N-terminal domain of mtra
Analyse Structure of N-terminal domain of mtra in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3NHZ
- Type
- protein
- Length
- 469 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Two component system transcriptional regulator mtra
- UniProt
- C6DXJ2
- Ligands
- MG
- Pockets
- 2 · best druggability 0.62
Structure
x-ray diffraction · 3 distinct chains · 44% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Two component system transcriptional regulator mtra | protein | 117 | 44% helix, 22% strand | C6DXJ2 |
| B | Two component system transcriptional regulator mtra | protein | 116 | 43% helix, 22% strand | C6DXJ2 |
| C, D | Two component system transcriptional regulator mtra | protein | 118 | 44% helix, 22% strand | C6DXJ2 |
Ligands and binding sites
- MG · Magnesium ion · metal · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 355 | 0.62 | 0.78 | 45 | empty |
| 2 | 75 | 0.37 | 0.76 | 14 | empty |
Interfaces
2 interfaces between chains.
- A–C · 518 Ų buried · 11 hydrogen bonds · protein-protein
- A–D · 406 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 3NHZ · Structure of N-terminal Domain of MtrA · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C6DXJ2
- Elsewhere: RCSB PDB 3NHZ · PDBe 3NHZ · UniProt C6DXJ2
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