Research workbench
1.8 ångström structure of intact native wild-type alpha-1-antitrypsin
Analyse 1.8 ångström structure of intact native wild-type alpha-1-antitrypsin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3NE4
- Type
- protein
- Length
- 370 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alpha-1-antitrypsin
- UniProt
- P01009
- Pockets
- 4 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-1-antitrypsin | protein | 370 | 29% helix, 31% strand | P01009 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 122 | 0.58 | 0.84 | 25 | empty |
| 2 | 78 | 0.54 | 0.86 | 19 | empty |
| 3 | 74 | 0.36 | 0.77 | 15 | empty |
| 4 | 73 | 0.30 | 0.73 | 20 | empty |
Compared structures
- 3NE4 · 1.8 Angstrom structure of intact native wild-type alpha-1-antitrypsin · the same entry in another collection · chain A against A, TM-score 1.00
- P01009 · AlphaFold monomer V2.0 prediction for alpha-1-antitrypsin (P01009) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01009
- Elsewhere: RCSB PDB 3NE4 · PDBe 3NE4 · UniProt P01009
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