Research workbench

NGOL

Analyse NGOL in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3NCV
Type: protein
Length: 375 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA mismatch repair protein mutl
UniProt: Q5F8M6
Pockets: 2 · best druggability 0.38

Structure

x-ray diffraction · 2 distinct chains · 41% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein mutl	protein	187	40% helix, 25% strand	Q5F8M6
B	DNA mismatch repair protein mutl	protein	188	41% helix, 25% strand	Q5F8M6

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.38	0.79	15	empty
2	56	0.32	0.76	15	empty

Interfaces

1 interface between chains.

A–B · 1190 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

3NCV · NgoL · the same entry in another collection · chain A against A, TM-score 1.00
Q5F8M6 · AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (Q5F8M6) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5F8M6
Elsewhere: RCSB PDB 3NCV · PDBe 3NCV · UniProt Q5F8M6

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