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Crystal structure of MAP kinase from plasmodium berghei, PB000659.00.0

Analyse Crystal structure of MAP kinase from plasmodium berghei, PB000659.00.0 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3N9X
Type: protein
Length: 748 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphotransferase
UniProt: Q4Z5A3
Pockets: 11 · best druggability 0.84

Structure

x-ray diffraction · 2 distinct chains · 39% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphotransferase	protein	374	38% helix, 13% strand	Q4Z5A3
B	Phosphotransferase	protein	374	40% helix, 13% strand	Q4Z5A3

Ligands and binding sites

GOL · Glycerol · additive · 7 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1177	0.84	0.85	123	GOL
2	116	0.67	0.90	23	GOL
3	170	0.54	0.80	26	empty
4	75	0.52	0.85	19	empty
5	75	0.47	0.83	16	empty

Interfaces

1 interface between chains.

A–B · 1961 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

3N9X · Crystal structure of Map Kinase from plasmodium berghei, PB000659.00.0 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4Z5A3
Elsewhere: RCSB PDB 3N9X · PDBe 3N9X · UniProt Q4Z5A3

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