Research workbench
Crystal structure of human pituitary adenylate cyclase 1 receptor- short N-terminal extracellular domain
Analyse Crystal structure of human pituitary adenylate cyclase 1 receptor- short… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3N94
- Type
- protein
- Length
- 466 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fusion protein of maltose-binding periplasmic protein and pituitary adenylate cyclase 1…
- UniProt
- P0AEX9, B8ZZK3
- Ligands
- GLC, SO4
- Pockets
- 4 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fusion protein of maltose-binding periplasmic protein and pituitary adenylate cyclase 1 receptor-short | protein | 466 | 45% helix, 21% strand | P0AEX9, B8ZZK3 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 973 | 0.80 | 0.81 | 78 | GLC, SO4 |
| 2 | 75 | 0.39 | 0.78 | 18 | empty |
| 3 | 84 | 0.38 | 0.77 | 18 | empty |
| 4 | 91 | 0.35 | 0.74 | 18 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 3N94 · Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AEX9
- Every structure of UniProt B8ZZK3
- Elsewhere: RCSB PDB 3N94 · PDBe 3N94 · UniProt P0AEX9 · UniProt B8ZZK3
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