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Crystal structure of HP67 H41F - P61

Analyse Crystal structure of HP67 H41F - P61 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3MYA
Type: protein
Length: 131 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Villin-1
UniProt: P02640
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 2 distinct chains · 53% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Villin-1	protein	67	54% helix, 0% strand	P02640
B	Villin-1	protein	64	53% helix, 0% strand	P02640

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.32	0.75	18	empty

Interfaces

1 interface between chains.

A–B · 534 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

3MYA · Crystal Structure of HP67 H41F - P61 · the same entry in another collection · chain A against A, TM-score 1.00
P02640 · AlphaFold monomer V2.0 prediction for villin-1 (P02640) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02640
Elsewhere: RCSB PDB 3MYA · PDBe 3MYA · UniProt P02640

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