Research workbench
Crystal structure of the rmi core complex
Analyse Crystal structure of the rmi core complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3MXN
- Type
- protein
- Length
- 282 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Recq-mediated genome instability protein 1; Recq-mediated genome instability protein 2
- UniProt
- Q9H9A7, Q96E14
- Ligands
- BEN
- Pockets
- 5 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Recq-mediated genome instability protein 1 | protein | 151 | 41% helix, 28% strand | Q9H9A7 |
| B | Recq-mediated genome instability protein 2 | protein | 131 | 19% helix, 39% strand | Q96E14 |
Ligands and binding sites
- BEN · Benzamidine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.41 | 0.78 | 16 | empty |
| 2 | 92 | 0.35 | 0.74 | 15 | empty |
| 3 | 53 | 0.35 | 0.78 | 14 | empty |
| 4 | 79 | 0.34 | 0.75 | 17 | empty |
| 5 | 51 | 0.31 | 0.76 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1345 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 3MXN · Crystal structure of the RMI core complex · the same entry in another collection · chain A against A, TM-score 1.00
- Q96E14 · AlphaFold monomer V2.0 prediction for recq-mediated genome instability protein 2 (Q96E14) · a predicted model of the same protein · chain B against A, TM-score 0.99
- Q9H9A7 · AlphaFold monomer V2.0 prediction for recq-mediated genome instability protein 1 (Q9H9A7) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H9A7
- Every structure of UniProt Q96E14
- Elsewhere: RCSB PDB 3MXN · PDBe 3MXN · UniProt Q9H9A7 · UniProt Q96E14
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.