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Graded expression of zinc-responsive genes through two regulatory zinc-binding sites in zur

Analyse Graded expression of zinc-responsive genes through two regulatory zinc-binding… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3MWM
Type: protein
Length: 252 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative metal uptake regulation protein
UniProt: Q9L2H5
Ligands: ZN
Pockets: 4 · best druggability 0.35

Structure

x-ray diffraction · 2 distinct chains · 42% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative metal uptake regulation protein	protein	127	42% helix, 18% strand	Q9L2H5
B	Putative metal uptake regulation protein	protein	125	42% helix, 18% strand	Q9L2H5

Ligands and binding sites

ZN · Zinc ion · metal · 6 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.35	0.79	17	empty
2	54	0.33	0.78	19	empty
3	71	0.29	0.73	22	empty
4	60	0.25	0.73	15	empty

Compared structures

3MWM · Graded expression of zinc-responsive genes through two regulatory zinc-binding sites in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9L2H5
Elsewhere: RCSB PDB 3MWM · PDBe 3MWM · UniProt Q9L2H5

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