Research workbench
Crystallographic analysis of the cystosolic CU/ZN superoxide dismutase from taenia solium
Analyse Crystallographic analysis of the cystosolic CU/ZN superoxide dismutase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3MND
- Type
- protein
- Length
- 304 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Superoxide dismutase [cu-zn]
- EC
- 1.15.1.1
- UniProt
- Q8WRF5
- Ligands
- ZN, CU
- Pockets
- 2 · best druggability 0.47
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Superoxide dismutase [cu-zn] (EC 1.15.1.1) | protein | 152 | 7% helix, 42% strand | Q8WRF5 |
Ligands and binding sites
- ZN · Zinc ion · metal · 5 copies · chains A, B
- CU · Copper (II) ion · metal · 2 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 161 | 0.47 | 0.76 | 20 | empty |
| 2 | 144 | 0.41 | 0.74 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 708 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 3MND · Crystallographic analysis of the cystosolic cu/zn Superoxide dismutase from taenia solium · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WRF5
- Elsewhere: RCSB PDB 3MND · PDBe 3MND · UniProt Q8WRF5
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