Research workbench
2OUF-2X, a designed knotted protein
Analyse 2OUF-2X, a designed knotted protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3MLG
- Type
- protein
- Length
- 322 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 2X chimera of helicobacter pylori protein HP0242
- UniProt
- O25025
- Pockets
- 3 · best druggability 0.38
Structure
x-ray diffraction · 1 distinct chain · 86% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 2X chimera of helicobacter pylori protein HP0242 | protein | 161 | 86% helix, 0% strand | O25025 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 95 | 0.38 | 0.75 | 17 | empty |
| 2 | 84 | 0.36 | 0.76 | 21 | empty |
| 3 | 67 | 0.28 | 0.73 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 618 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 3MLG · 2ouf-2x, a designed knotted protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O25025
- Elsewhere: RCSB PDB 3MLG · PDBe 3MLG · UniProt O25025
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.