Research workbench
Crystal structure of toxic shock syndrome toxin 1 (tsst-1) in complex with the human T cell receptor beta chain VBETA2.1 (ep-8)
Analyse Crystal structure of toxic shock syndrome toxin 1 (tsst-1) in complex with the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3MFG
- Type
- protein
- Length
- 301 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Toxic shock syndrome toxin-1; V_SEGMENT translation product
- UniProt
- Q7A4K7
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Toxic shock syndrome toxin-1 | protein | 191 | 16% helix, 44% strand | Q7A4K7 |
| B | V_SEGMENT translation product | protein | 110 | 3% helix, 57% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 137 | 0.46 | 0.77 | 22 | SO4 |
| 2 | 76 | 0.36 | 0.77 | 17 | GOL |
| 3 | 71 | 0.35 | 0.76 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 889 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3MFG · Crystal structure of Toxic Shock Syndrome Toxin 1 (TSST-1) in complex with the human T… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7A4K7
- Elsewhere: RCSB PDB 3MFG · PDBe 3MFG · UniProt Q7A4K7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.