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Crystal structure of the matrix protein 1 from influenza a virus (A/CALIFORNIA/04/2009 (H1N1))

Analyse Crystal structure of the matrix protein 1 from influenza a virus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3MD2
Type
protein
Length
568 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Matrix protein 1
UniProt
C3W5Z1
Pockets
2 · best druggability 0.29

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, DMatrix protein 1protein14271% helix, 0% strandC3W5Z1

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1720.290.7317empty
2500.230.7215empty

Interfaces

3 interfaces between chains.

  • A–D · 763 Ų buried · 10 hydrogen bonds · protein-protein
  • B–C · 759 Ų buried · 10 hydrogen bonds · protein-protein
  • B–D · 130 Ų buried · 4 hydrogen bonds · protein-protein

Compared structures

  • 3MD2 · Crystal structure of the matrix protein 1 from influenza A virus (A/California/04/2009… · the same entry in another collection · chain A against A, TM-score 1.00

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