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Crystal structure of bacillus subtilis lon N-terminal domain

Analyse Crystal structure of bacillus subtilis lon N-terminal domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3M65
Type: protein
Length: 408 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ATP-dependent protease la 1
EC: 3.4.21.53
UniProt: P37945
Pockets: 4 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	ATP-dependent protease la 1 (EC 3.4.21.53)	protein	204	42% helix, 30% strand	P37945

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	954	0.74	0.77	68	empty
2	56	0.49	0.86	15	empty
3	53	0.33	0.77	11	empty
4	75	0.32	0.74	18	empty

Interfaces

1 interface between chains.

A–B · 3662 Å² buried · 32 hydrogen bonds · protein-protein

Compared structures

3M65 · Crystal structure of Bacillus subtilis Lon N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
P37945 · AlphaFold monomer V2.0 prediction for lon protease 1 (P37945) · a predicted model of the same protein · chain A against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P37945
Elsewhere: RCSB PDB 3M65 · PDBe 3M65 · UniProt P37945

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