Research workbench
Crystal structure of the btb domain from the miz-1/ZBTB17 transcription regulator
Analyse Crystal structure of the btb domain from the miz-1/ZBTB17 transcription… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3M52
- Type
- protein
- Length
- 234 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Zinc finger and btb domain-containing protein 17
- UniProt
- Q13105
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 59% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Zinc finger and btb domain-containing protein 17 | protein | 117 | 59% helix, 11% strand | Q13105 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 107 | 0.43 | 0.77 | 18 | empty |
| 2 | 100 | 0.41 | 0.76 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1607 Ų buried · 21 hydrogen bonds · protein-protein
Compared structures
- 3M52 · Crystal structure of the BTB domain from the Miz-1/ZBTB17 transcription regulator · the same entry in another collection · chain A against A, TM-score 1.00
- Q13105 · AlphaFold monomer V2.0 prediction for zinc finger and btb domain- containing protein 17… · a predicted model of the same protein · chain A against A, TM-score 0.67
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13105
- Elsewhere: RCSB PDB 3M52 · PDBe 3M52 · UniProt Q13105
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