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1.75 ångström resolution crystal structure of an orotate phosphoribosyltransferase from bacillus anthracis str. 'ames ancestor'

Analyse 1.75 ångström resolution crystal structure of an orotate… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3M3H
Type: protein
Length: 202 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Orotate phosphoribosyltransferase
EC: 2.4.2.10
UniProt: Q81WF6
Ligands: CL
Pockets: 2 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Orotate phosphoribosyltransferase (EC 2.4.2.10)	protein	202	49% helix, 21% strand	Q81WF6

Ligands and binding sites

CL · Chloride ion · ion · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	138	0.45	0.77	25	empty
2	62	0.29	0.74	16	CL

Compared structures

3M3H · 1.75 Angstrom resolution crystal structure of an orotate phosphoribosyltransferase from… · the same entry in another collection · chain A against A, TM-score 1.00
Q81WF6 · AlphaFold monomer V2.0 prediction for orotate phosphoribosyltransferase (Q81WF6) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q81WF6
Elsewhere: RCSB PDB 3M3H · PDBe 3M3H · UniProt Q81WF6

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