Research workbench
Crystal structure of putative snoal-like polyketide cyclase (YP_563807.1) from shewanella denitrificans os-217 at 1.70 a resolution
Analyse Crystal structure of putative snoal-like polyketide cyclase (YP_563807.1) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3LZA
- Type
- protein
- Length
- 547 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative snoal-like polyketide cyclase
- UniProt
- Q12KE2
- Pockets
- 7 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, D | Putative snoal-like polyketide cyclase | protein | 137 | 31% helix, 44% strand | Q12KE2 |
| C | Putative snoal-like polyketide cyclase | protein | 136 | 31% helix, 44% strand | Q12KE2 |
Pockets
7 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 249 | 0.71 | 0.85 | 25 | empty |
| 2 | 225 | 0.71 | 0.86 | 23 | empty |
| 3 | 268 | 0.70 | 0.85 | 28 | empty |
| 4 | 262 | 0.69 | 0.84 | 23 | empty |
| 5 | 69 | 0.52 | 0.86 | 16 | empty |
Interfaces
3 interfaces between chains.
- A–B · 784 Ų buried · 2 hydrogen bonds · protein-protein
- C–D · 783 Ų buried · 2 hydrogen bonds · protein-protein
- B–C · 146 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 16 modified (engineered).
Compared structures
- 3LZA · Crystal structure of Putative SnoaL-like polyketide cyclase (YP_563807.1) from SHEWANELLA… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12KE2
- Elsewhere: RCSB PDB 3LZA · PDBe 3LZA · UniProt Q12KE2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.