Research workbench
Crystal structure of the periplasmic domain of cadc in the presence of K2RECL6
Analyse Crystal structure of the periplasmic domain of cadc in the presence of K2RECL6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3LYA
- Type
- protein
- Length
- 318 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional activator cadc
- UniProt
- P23890
- Ligands
- RHE
- Pockets
- 3 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 58% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional activator cadc | protein | 318 | 58% helix, 14% strand | P23890 |
Ligands and binding sites
- RHE · rhenium (IV) hexachloride · ligand · 16 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 247 | 0.84 | 0.96 | 31 | RHE |
| 2 | 74 | 0.40 | 0.79 | 17 | empty |
| 3 | 50 | 0.31 | 0.77 | 13 | RHE |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3LYA · Crystal structure of the periplasmic domain of CadC in the presence of K2ReCl6 · the same entry in another collection · chain A against A, TM-score 1.00
- P23890 · AlphaFold monomer V2.0 prediction for transcriptional activator cadc (P23890) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23890
- Elsewhere: RCSB PDB 3LYA · PDBe 3LYA · UniProt P23890
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