Research workbench
Crystal structure of mutant D471E of the periplasmic domain of cadc
Analyse Crystal structure of mutant D471E of the periplasmic domain of cadc in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3LY8
- Type
- protein
- Length
- 323 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional activator cadc
- UniProt
- P23890
- Pockets
- 3 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 58% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional activator cadc | protein | 323 | 58% helix, 12% strand | P23890 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 220 | 0.84 | 0.97 | 33 | empty |
| 2 | 77 | 0.40 | 0.79 | 17 | empty |
| 3 | 89 | 0.37 | 0.76 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3LY8 · Crystal structure of mutant D471E of the periplasmic domain of CadC · the same entry in another collection · chain A against A, TM-score 1.00
- P23890 · AlphaFold monomer V2.0 prediction for transcriptional activator cadc (P23890) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23890
- Elsewhere: RCSB PDB 3LY8 · PDBe 3LY8 · UniProt P23890
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