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Crystal structure of the periplasmic domain of cadc

Analyse Crystal structure of the periplasmic domain of cadc in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3LY7
Type: protein
Length: 322 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional activator cadc
UniProt: P23890
Pockets: 5 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 58% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional activator cadc	protein	322	58% helix, 12% strand	P23890

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	215	0.83	0.96	33	empty
2	73	0.40	0.79	17	empty
3	56	0.35	0.78	14	empty
4	65	0.31	0.75	13	empty
5	54	0.27	0.74	14	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

3LY7 · Crystal structure of the periplasmic domain of CadC · the same entry in another collection · chain A against A, TM-score 1.00
P23890 · AlphaFold monomer V2.0 prediction for transcriptional activator cadc (P23890) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23890
Elsewhere: RCSB PDB 3LY7 · PDBe 3LY7 · UniProt P23890

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