Research workbench
Structure of probable glutathione S-TRANSFERASE(PP0183) from pseudomonas putida
Analyse Structure of probable glutathione S-TRANSFERASE(PP0183) from pseudomonas putida in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3LXZ
- Type
- protein
- Length
- 870 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutathione S-transferase family protein
- UniProt
- Q88RE7
- Pockets
- 11 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 61% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Glutathione S-transferase family protein | protein | 218 | 61% helix, 9% strand | Q88RE7 |
| B, D | Glutathione S-transferase family protein | protein | 217 | 60% helix, 9% strand | Q88RE7 |
Pockets
11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 980 | 0.78 | 0.80 | 86 | empty |
| 2 | 200 | 0.68 | 0.86 | 33 | empty |
| 3 | 282 | 0.56 | 0.76 | 34 | empty |
| 4 | 338 | 0.55 | 0.74 | 48 | empty |
| 5 | 276 | 0.55 | 0.76 | 32 | empty |
Interfaces
3 interfaces between chains.
- C–D · 1719 Ų buried · 22 hydrogen bonds · protein-protein
- A–D · 580 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 547 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 32 modified (engineered).
Compared structures
- 3LXZ · Structure of probable Glutathione S-transferase(PP0183) from Pseudomonas putida · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q88RE7
- Elsewhere: RCSB PDB 3LXZ · PDBe 3LXZ · UniProt Q88RE7
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