Research workbench
Crystal structure of CREN7-dsdna complex
Analyse Crystal structure of CREN7-dsdna complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3LWI
- Type
- protein + DNA
- Length
- 148 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chromatin protein CREN7; DNA (5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3')
- UniProt
- Q97ZE3
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 0% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Chromatin protein CREN7 | protein | 58 | 0% helix, 43% strand | Q97ZE3 |
| C, D, E, F | DNA (5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3') | dna | 8 | — | — |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 453 | 0.64 | 0.77 | 42 | empty |
| 2 | 117 | 0.40 | 0.76 | 15 | empty |
Interfaces
8 interfaces between chains.
- A–C · 553 Ų buried · 9 hydrogen bonds · protein-nucleic
- B–E · 534 Ų buried · 10 hydrogen bonds · protein-nucleic
- A–D · 391 Ų buried · 3 hydrogen bonds · protein-nucleic
- B–F · 389 Ų buried · 3 hydrogen bonds · protein-nucleic
- E–F · 379 Ų buried · 35 hydrogen bonds · nucleic-nucleic
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q97ZE3
- Elsewhere: RCSB PDB 3LWI · PDBe 3LWI · UniProt Q97ZE3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.