Research workbench

Flavoprotein 390

Analyse Flavoprotein 390 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1FVP
Type: protein
Length: 462 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flavoprotein 390
UniProt: P12745
Ligands: FMA
Pockets: 7 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Flavoprotein 390	protein	231	43% helix, 18% strand	P12745

Ligands and binding sites

FMA · 6-(3-tetradecanoic acid) flavine mononucleotide · ligand · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	750	0.82	0.85	75	FMA
2	426	0.73	0.83	60	FMA
3	137	0.66	0.87	23	FMA
4	171	0.65	0.84	23	FMA
5	236	0.52	0.76	23	empty

Interfaces

1 interface between chains.

A–B · 1517 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

1FVP · Flavoprotein 390 · the same entry in another collection · chain A against A, TM-score 1.00
P12745 · AlphaFold monomer V2.0 prediction for non-fluorescent flavoprotein (P12745) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P12745
Elsewhere: RCSB PDB 1FVP · PDBe 1FVP · UniProt P12745

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.